Gruppo Di Nardo

CENTRO DI RICERCA
Laboratorio di Cardiologia molecolare e cellulare, universita’ di roma “tor vergata”, ITALIA
Group Leader
Paolo Di Nardo
dinardo@uniroma2.it
Componenti
 
 
Marilena Minieri, Giancarlo Forte, Francesca Pagliari, Stefania Pagliari, Eugenio Magnani, Giorgia Nardone, Sara Romanazzo, Roberta Fiaccavento, Felicia Carotenuto.
Interessi Scientifici
 
 
Studi di base in vitro e in vivo sulla biologia delle cellule staminali mesenchimali e residenti cardiache.
Riparazione del miocardio infartuato tramite cellule staminali adulte e scaffold biocompatibili e biodegradabili.
Interazione tra cellule staminali e matrici polimeriche.
Effetto degli acidi grassi poli-insaturi su cellule muscolari cardiache e scheletriche.
 
 
Attività Clinico/Assistenziale
 
 
Expertise
 
 
Estrazione, purificazione e coltura di cellule staminali da vari tessuti e loro differenziamento cardiaco su scaffold polimerici.
Coltura e differenziamento di cellule staminali in condizioni dinamiche.
Pubblicazioni caratterizzanti
 
 
1) Di Nardo P, Forte G, Ahluwalia A, Minieri M. Cardiac Stem Cells: Potency and Control. Review. J Cell Physiol (2010) 224: 590-600.
2) MandoliC,Pagliari F, Pagliari S,Forte G, Di Nardo P, Licoccia S, Traversa E. Stem cell aligned growth induced by CeO2 nanoparticles in PLGA scaffolds with improved bioactivity for regenerative medicine. Adv Funct Mater (2010) 20: 1617-1624
3) Forte G, Franzese O, Pagliari S, Pagliari F, Cossa P, Laudisi A, Di Francesco AM, Fiaccavento R, Carotenuto F, Bonmassar E, Fiaccavento R, Minieri M, Di Nardo P. Interfacing Sca-1pos Mesenchymal Stem Cells with Biocompatible Scaffolds with Different Chemical Composition and Geometry. J Biomed Biotechnol(2009) doi: 10.1155/2009/910610.
4) Forte G, Carotenuto F, Pagliari F, Pagliari S, Cossa P, Fiaccavento R, Ahluwalia A, Vozzi G, Vinci B, Serafino A, Rinaldi A, Traversa E, Carosella L, Minieri M, Di Nardo P. Criticatility of the biological and physical stimuli array inducing resident stem cell determination. Stem Cells (2008) 26: 2093-2103.
5) Soliman S, Pagliari S, Rinaldi A, Forte G, Fiaccavento R, Pagliari F, Minieri M, Di Nardo P, Licoccia S, Traversa E. Multiscale 3D Scaffolds for Soft Tissue Engineering via Multimodal Electrospinning. Acta Biomaterialia(2010) 6: 1227-1237.
Stumentazioni disponibili
 
 
Camera di coltura cellule attrezzata; strumenti per la biologia molecolare e cellulare (RT-PCR, FACS, western blot, MACS,…), criostato.

 
 
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